49ers vs. Seahawks Week 6 Predictions, Odds and Stats

placeholder image

Our computer model predicts the Seattle Seahawks will take down the San Francisco 49ers on Thursday, Oct. 10 at 8:15 p.m. ET. For a complete projection on the game at Lumen Field, which includes our prediction on the spread, over/under, and final score, keep reading.

Watch Thursday Night Football exclusively on Amazon Prime. Use our link to sign up for Prime Video.

49ers vs. Seahawks Game Info and TV Channel

Catch every NFL touchdown with NFL RedZone on Fubo.

49ers vs. Seahawks Odds and Betting Info

  • Spread favorite: 49ers (-3.5)
  • Moneyline: 49ers (-187), Seahawks (+157)
  • Total: 49.5 points

49ers vs. Seahawks Prediction

  • Pick ATS: Seahawks (+3.5)
  • Pick OU: Under (49.5)

Prediction:

Seahawks 24 - 49ers 23

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

    See how these predictions pan out and sign up for NFL RedZone on Fubo to catch every score on Sundays this fall.

    49ers vs. Seahawks Betting Insights

    • The 49ers have covered twice in five games with a spread this season.
    • The Seahawks have a record of just 1-3-1 against the spread this season.
    • San Francisco has been favored by 3.5 points or more five times this season, and covered the spread in two of those games.
    • Seattle has not covered the spread when an underdog by 3.5 points or more this year (in one opportunity).
    • So far this season, three out of the 49ers' five games have gone over the point total.
    • Seahawks games have gone over the point total four out of five times this year.

    Looking for NFL tickets? Head to StubHub today and see your team live.


    Sponsored Content

    Sponsored Content