Photo: Ronald Martinez / Getty Images Sport / Getty Images
Los Angeles Rams quarterback Matthew Stafford has a tough matchup in Week 5 (Thursday at 8:15 p.m. ET), up against the San Francisco 49ers. The 49ers are giving up the sixth-fewest passing yards in the league, 165 per game.
This year, Stafford has thrown for 1,114 yards (278.5 per game) for Los Angeles, tossing eight touchdown passes with two picks. Stafford has tacked on -4 rushing yards on 10 carries while averaging -1.0 yards per contest.
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Stafford vs. the 49ers
- Stafford vs the 49ers (since 2021): 6 GP / 257.7 PASS YPG / 10 PASS TD
- San Francisco hasn't allowed an opposing quarterback to record 300 or more passing yards against them in an outing yet this year.
- The 49ers have allowed three players to throw one or more TDs in a game this season.
- San Francisco has allowed one player to throw at least two touchdowns in a matchup in 2025.
- The 49ers have given up at least three TD passes in an outing to one opposing QB this season.
- Stafford will square off against the NFL's sixth-ranked pass defense this week. The 49ers allow 165 passing yards per contest.
- Opponents of the 49ers have totaled five touchdowns through the air (1.3 per game). The 49ers' defense is seventh in the NFL in that category.
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Stafford Passing Insights
- So far this year, Stafford has hit the over on his passing yards prop total in three of four opportunities.
- The Rams have passed 56.1% of the time and run 43.9% this season. They rank 13th in the NFL in scoring.
- Stafford's 8.2 yards per attempt rank fifth in the NFL.
- Stafford has thrown for a touchdown in all four games this season, with more than one TD pass three times.
- He has scored eight of his team's 11 offensive touchdowns this season (72.7%).
- Stafford has passed 20 times out of his 136 total attempts while in the red zone (51.3% of his team's red zone plays).
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Stafford's Recent Performance
| Opponent | Date | Week | Passing Stats | Rushing Stats |
|---|---|---|---|---|
| vs. Colts | 9/28/2025 | Week 4 | 29-for-41 / 375 YDS / 3 TDs / 0 INTs | 4 ATT / 4 YDS / 0 TDs |
| vs. Eagles | 9/21/2025 | Week 3 | 19-for-33 / 196 YDS / 2 TDs / 1 INT | 0 ATT / 0 YDS / 0 TDs |
| vs. Titans | 9/14/2025 | Week 2 | 23-for-33 / 298 YDS / 2 TDs / 1 INT | 2 ATT / -6 YDS / 0 TDs |
| vs. Texans | 9/7/2025 | Week 1 | 21-for-29 / 245 YDS / 1 TD / 0 INTs | 4 ATT / -2 YDS / 0 TDs |