Photo: Ronald Martinez / Getty Images Sport / Getty Images
The Los Angeles Lakers (6-2) are 1.5-point underdogs as they attempt to continue a four-game win streak when they host the San Antonio Spurs (5-1) on Wednesday, November 5, 2025 at Crypto.com Arena. The game airs at 10 p.m. ET on ESPN, SportsNet LA, and FDSSW.
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Listen to the game on News Radio 1200 WOAI
Spurs vs. Lakers Predictions for Wednesday
Our computer projections model for this encounter expects a final tally of Lakers 118, Spurs 114.
- Moneyline Pick: Lakers (+101)
- Total Pick: Over 227.5 (computer predicts 231.4 points)
- Pick ATS: Lakers (+1.5)
Recent Spurs vs. Lakers Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 3/17/2025 | Lakers | -9.5 | 230.5 | -444 | +341 | 125-109 LAL |
| 1/13/2025 | Lakers | -4 | 221.5 | -186 | +154 | 126-102 SA |
| 11/27/2024 | Lakers | -1.5 | 227.5 | -134 | +112 | 119-101 LAL |
| 11/15/2024 | Lakers | -2.5 | 228 | -138 | +117 | 120-115 LAL |
Spurs 2025-26 Betting Trends
- San Antonio is 2-2-2 against the spread this season.
- In games they have played as at least 1.5-point favorites this season, the Spurs are 1-2-2 against the spread.
- In San Antonio's eight games with a set total, two have hit the over.
- This season, the Spurs have won four out of the five games in which they've been favored.
- San Antonio has a record of 4-1 when it's favored by -121 or more by oddsmakers this season.
Lakers 2025-26 Betting Trends
- Los Angeles is 6-2-0 ATS this year.
- The Lakers are 4-2 against the spread when an underdog by 1.5 points or more this year.
- Los Angeles has hit the over in seven of its eight games with a set total (87.5%).
- The Lakers have been the underdog on the moneyline six total times this season. They've finished 4-2 in those games.
- When it has played as a moneyline underdog with odds of +101 or longer, Los Angeles has gone 4-2 (66.7%).
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Spurs vs. Lakers Injury Report
Spurs
Spurs:
Dylan Harper: Out (Calf),
De'Aaron Fox: Out (Hamstring),
Kelly Olynyk: Questionable (Heel),
Jeremy Sochan: Questionable (Wrist),
Lindy Waters III: Questionable (Eye),
Luke Kornet: Out (Ankle)
Lakers
Lakers:
Maxi Kleber: Out (Oblique),
Austin Reaves: Out (Groin),
LeBron James: Out (Nerve),
Adou Thiero: Out (Knee),
Gabe Vincent: Out (Ankle)
Spurs vs. Lakers Game Time and TV Channel
- Game day: Wednesday, November 5, 2025
- Game time: 10 p.m. ET
- TV channel: ESPN, SportsNet LA, and FDSSW
- Location: Los Angeles, California
- Arena: Crypto.com Arena
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
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